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Digoxin passes into breast milkWhile there have been no reports of harm to nursing infantsconsult your doctor before breast-feeding.

Some products have ingredients that could worsen your heart failureTell your pharmacist what products you are usingand ask how to use them safelyespecially cough-and-cold productsdiet aidsor NSAIDs such as ibuprofen/naproxen

Digoxin is primarily excreted by the kidneysthereforepatients with impaired renal function require smaller than usual maintenance doses of digoxinsee DOSAGE AND ADMINISTRATIONBecause of the prolonged elimination half-lifea longer period of time is required to achieve an initial or new steady-state serum concentration in patients with renal impairment than in patients with normal renal functionIf appropriate care is not taken to reduce the dose of digoxinsuch patients are at high risk for toxicityand toxic effects will last longer in such patients than in patients with normal renal function.

Decreased Cardiac Output in Patients With Preserved Left Ventricular Systolic Function.

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